GMP Standard Synthesis Hot Cell for Radiopharmaceutical Production with Lead Equivalent Shielding and Stainless Steel Structure

مكان المنشأ الصين
اسم العلامة التجارية Jovi
رقم الموديل JVVMed-HC
الوثيقة JVVMEG-HCFH50-PET.pdf
الحد الأدنى لكمية 1 مجموعة
الأسعار $35000~$95623
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تفاصيل المنتج
نظافة فئة ABC ما يعادلها 10mmpb 20mmpb 50mmpb 100mmpb
مادة هيكل الفولاذ المقاوم للصدأ ، الطوب الرصاص نظام التشغيل السيطرة على الذكاء الاصطناعي
طريقة التنقية مرشح الكربون النشط ، ترشيح HEPA ، طريقة التطهير ضوء الأشعة فوق البنفسجية والأوزون
خيارات بديلة موزع يدوي ، موزع أوتوماتيكي اسم المنتج الخلية الساخنة للتخليق لخط الإنتاج الإشعاعي GMP Standard
إبراز

Lead Equivalent Shielding Synthesis Hot Cell,Stainless Steel Structure Radiopharmaceutical Production Hot Cell,Lead Bricks Shielding Hot Cell

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Stainless Steel Structure Radiopharmaceutical Production Hot Cell

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Lead Bricks Shielding Hot Cell

اترك رسالة
منتوج وصف
GMP Standard Synthesis Hot Cell for Radiopharmaceutical Production
The synthesis hot cell (also known as a synthesis shielding box or hot cell) is the core equipment in the radiopharmaceutical production process. Its design ensures the safety of operators, the environment, and the product itself, featuring Class A/B/C cleanliness standards with real-time dose monitoring, HEPA filtration, and active carbon filtration in a negative pressure environment.
Key Characteristics
Radiation Shielding
The most critical feature, effectively shielding high-energy gamma rays or neutrons emitted by radionuclides.
  • Materials: High-density lead (Pb) bricks or plates as primary shielding material, with lead glass for viewing windows and steel for structural support
  • Thickness: Precisely calculated based on radionuclide type and activity, ranging from a few centimeters to several tens of centimeters to ensure radiation dose rates remain below safe regulatory limits (typically below 2.5 μSv/h)
Containment, Negative Pressure & HEPA Filtration
  • Containment: Highly sealed system to prevent leakage of radioactive aerosols or volatile substances
  • Negative Pressure System: Maintains internal air pressure lower than surrounding room to prevent contaminant escape
  • HEPA Filtration: Multiple-stage High-Efficiency Particulate Air filters capture radioactive particles, with activated carbon filters for volatile radionuclides
Remote Manipulation & Automation
Enables operation without direct hand contact with internal items:
  • Manipulators: Master-slave manipulators or electric-powered manipulators controlled by joysticks/touchscreens
  • Full Automation Systems: Computer-program-controlled automated modules perform entire synthesis processes, reducing human intervention and improving repeatability
Product Protection & Aseptic Environment
Meets stringent standards for sterile, pyrogen-free radiopharmaceuticals:
  • Internal Environment: Clean environment meeting Grade C or A (ISO Class 7 or 5) standards
  • Transfer Systems: Dedicated pass-through boxes with interlocking mechanisms and UV lights
  • Surface Materials: Smooth, seamless stainless steel surfaces resistant to frequent disinfection
Shielding Viewing Window
Special lead glass windows provide necessary transparency while offering equivalent radiation shielding to lead walls, typically multi-layered and very thick.
Utilities Integration
Comprehensive utility interfaces for production:
  • Electrical: Powers instruments, manipulators, lighting
  • Pneumatic: Supplies compressed air or inert gases
  • Vacuum: Used for filtration or liquid transfer
  • Cooling/Ventilation: Independent systems to maintain stable temperature
Monitoring & Safety Systems
  • Radiation detectors continuously monitor internal levels
  • Pressure monitoring displays negative pressure status with alarm triggers
  • Temperature and smoke sensors prevent safety incidents
  • Safety interlocks on doors and pass-through boxes prevent radiation leakage
A radiopharmaceutical synthesis hot cell is a complex engineering system integrating radiation shielding, containment, remote/automated operation, and sterile control. Modern designs emphasize high integration, automation, and modularization to reduce operational complexity and radiation exposure risks while maintaining strict GMP quality standards.